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Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 into the active metabolite N-desmethyldiazepam, and is also hydroxylated by CYP3A4 to your active metabolite temazepam.Will not get rid of prescription drugs in wastewater (e.g. down the sink or from the rest room) or in home rubbish. Request your pharmacist tips on how to get rid of remedies